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A YscF, LcrV, YopB, and YopD, respectively. YopB is presumed to represent the primary component of a translocation pore that traverses the eukaryotic membrane and allows passage of effectors into the host cytosol. Osmoprotection (21) and dye permeabilization (39) studies indirectly indicate formation of YopB-dependent pores. The Shigella homolog IpaB is capable of oligomerization and depends on hy

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